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| |
Empagliflozin
|
Sitagliptin
|
p value
|
|---|
|
SRS
|
|
Baseline
|
0.43 ± 0.68
|
0.80 ± 1.82
|
0.388
|
|
12 weeks
|
0.19 ± 0.40
|
0.43 ± 1.54
|
0.496
|
|
Change
|
−0.24 ± 0.89
|
−0.35 ± 0.67
|
0.653
|
|
Intragroup p value
|
0.234
|
0.031*
| |
|
Washout rate (%)
|
|
Baseline
|
11.6 ± 3.9
|
11.3 ± 4.9
|
0.858
|
|
12 weeks
|
10.7 ± 3.7
|
12.1 ± 4.1
|
0.238
|
|
Change
|
−0.9 ± 4.3
|
0.7 ± 3.7
|
0.200
|
|
Intragroup p Value
|
0.354
|
0.379
| |
|
Early H/M ratio
|
|
Baseline
|
2.65 ± 0.36
|
2.57 ± 0.31
|
0.496
|
|
12 weeks
|
2.58 ± 0.39
|
2.56 ± 0.36
|
0.879
|
|
Change
|
−0.07 ± 0.24
|
−0.01 ± 0.23
|
0.460
|
|
Intragroup p value
|
0.206
|
0.806
| |
|
Delay H/M ratio
|
|
Baseline
|
2.36 ± 0.33
|
2.32 ± 0.34
|
0.725
|
|
12 weeks
|
2.34 ± 0.30
|
2.32 ± 0.41
|
0.867
|
|
Change
|
−0.02 ± 0.22
|
−0.01 ± 0.19
|
0.811
|
|
Intragroup p value
|
0.657
|
0.890
| |
- Data are presented as the mean ± SD (n = 21 for both groups). p values < 0.05 indicate significant differences. Comparisons were performed by one-sample t-test in each group, and two-sample t-tests between groups. SRS: summed rest score, H/M: heart-to-mediastinal ratio. *p < 0.05
