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Propensity-matched patients with diabetes
Propensity-matched patients without diabetes
Medical therapy
Successful PCI
P value
Medical therapy
Successful PCI
P value
(n = 270)
(n = 135)
(n = 464)
(n = 232)
Age, years
65.2 ± 4.7
64.6 ± 9.1
0.648
63.7 ± 10.9
63.2 ± 9.9
0.340
Male
187 (69.3)
100 (74.1)
0.315
372 (80.5)
184 (79.7)
0.787
Smoking
102 (37.8)
55 (40.7)
0.564
65 (14.1)
26 (11.3)
0.301
Hypertension
197 (73.0)
96 (71.1)
0.694
302 (65.4)
151 (65.4)
1.000
Insulin-dependent DM
106 (39.3)
50 (37.0)
0.665
–
–
–
Dyslipidemia
213 (78.9)
102 (75.6)
0.447
330 (71.4)
162 (70.1)
0.722
Familial history o CAD
23 (8.5)
12 (8.9)
0.900
118 (25.5)
56 (24.2)
0.710
Previous MI
115 (42.6)
59 (43.7)
0.831
79 (17.1)
40 (17.3)
0.943
CKD
33 (12.2)
15 (11.1)
0.744
37 (8.0)
15 (6.5)
0.475
Heart failure
60 (22.2)
30 (22.2)
1.000
57 (12.3)
21 (9.1)
0.202
LVEF, %
52.1 ± 10.9
52.4 ± 9.8
0.764
54.0 ± 8.3
54.9 ± 7.6
0.876
Baseline medication
Aspirin
265 (98.1)
132 (97.8)
0.801
451 (97.6)
224 (97.0)
0.612
Clopidogrel
256 (94.8)
128 (94.8)
1.000
442 (95.7)
227 (98.3)
0.078
Statin
256 (94.8)
131 (97.0)
0.306
441 (95.5)
221 (95.7)
0.897
β blocker
196 (72.6)
103 (76.3)
0.424
369 (79.9)
188 (81.4)
0.636
ACEI or ARB
172 (63.7)
85 (63.0)
0.884
289 (62.6)
142 (61.5)
0.782
One CTO lesion
235 (87.0)
115 (85.2)
0.608
392 (84.8)
192 (83.1)
0.555
Two CTO lesions
33 (12.2)
19 (14.1)
0.599
63 (13.6)
35 (15.2)
0.589
LAD
85 (31.5)
51 (37.8)
0.206
175 (37.9)
89 (38.5)
0.868
LCX
73 (27.0)
38 (28.1)
0.813
120 (26.0)
62 (26.8)
0.807
RCA
143 (53.0)
62 (45.9)
0.182
232 (50.2)
113 (48.9)
0.747
Multivessel disease
221 (81.9)
105 (77.8)
0.329
360 (77.9)
154 (66.7)
0.001
Proximal or mid
170 (63.0)
94 (69.6)
0.184
341 (73.8)
170 (73.6)
0.159
CTO location
Blunt stump
85 (31.5)
33 (24.4)
0.142
183 (39.6)
74 (32.0)
0.052
Calcification
32 (11.9)
17 (12.6)
0.829
71 (15.4)
38 (16.5)
0.712
Bending > 45°
117 (43.3)
58 (43.0)
0.943
206 (44.6)
86 (37.2)
0.064
Length ≥ 20 mm
160 (59.3)
85 (63.0)
0.472
306 (66.2)
141 (61.0)
0.178
J-CTO score
1.43 ± 1.16
1.41 ± 0.98
0.216
1.63 ± 1.11
1.44 ± 1.05
0.139
SYNTAX score
23.7 ± 8.3
22.4 ± 7.9
0.658
24.2 ± 8.5
22.7 ± 7.8
0.504
Values are presented as the mean ± standard deviation or n (%)
ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin-receptor blocker, CAD coronary artery disease, CKD chronic kidney disease, CTO chronic total occlusion, J -CTO Japanese-chronic total occlusion, LAD left ascending coronary artery, LCX left circumflex coronary artery, LVEF left ventricular ejection fraction, MI myocardial infarction, PCI percutaneous coronary intervention, RCA right coronary artery