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| |
Anagliptin
|
Sitagliptin
|
P
|
|---|
|
n (M/F)
|
148 (89/59)
|
159 (93/66)
|
0.77
|
|
Age (years)
|
68 ± 9
|
68 ± 9
|
0.91
|
|
Body mass index
|
26.7 ± 3.9
|
25.8 ± 3.6
|
0.04
|
|
Waist circumference (cm)
|
94.2 ± 11.1
|
92.7 ± 9.8
|
0.24
|
|
Smoking habit
|
71 (48)
|
92 (58)
|
0.08
|
|
Alcohol drinking habit
|
58 (39)
|
67 (42)
|
0.60
|
|
Diagnosis
|
|
Hypertension
|
117 (79)
|
116 (73)
|
0.21
|
|
Coronary artery disease
|
68 (46)
|
71 (45)
|
0.82
|
|
Stroke
|
22 (15)
|
24 (15)
|
0.96
|
|
Medication
|
|
Dipeptidyl peptidase-4 inhibitora
|
122 (82)
|
128 (81)
|
0.66
|
|
Biguanide
|
74 (50)
|
71 (45)
|
0.35
|
|
Thiazolidinedione
|
22 (15)
|
29 (18)
|
0.43
|
|
α glucosidase inhibitor
|
19 (13)
|
27 (17)
|
0.31
|
|
Sulfonylurea
|
41 (28)
|
32 (20)
|
0.12
|
|
Glinide
|
7 (5)
|
2 (1)
|
0.09
|
|
Sodium–glucose cotransporter 2 inhibitor
|
25 (17)
|
16 (10)
|
0.08
|
|
Insulin
|
12 (8)
|
13 (8)
|
0.98
|
|
Statin
|
148 (100)
|
159 (100)
|
–
|
|
Strong statinb
|
118 (80)
|
121 (76)
|
0.44
|
|
Ezetimibe
|
16 (11)
|
11 (7)
|
0.23
|
|
Fibrate
|
9 (6)
|
7 (4)
|
0.51
|
|
Eicosapentaenoic acid
|
16 (11)
|
13 (8)
|
0.43
|
|
Angiotensin II receptor blocker
|
75 (51)
|
80 (50)
|
0.95
|
|
Angiotensin-converting enzyme inhibitor
|
18 (12)
|
10 (6)
|
0.07
|
|
Calcium channel blocker
|
72 (49)
|
68 (43)
|
0.30
|
|
β blocker
|
35 (24)
|
38 (24)
|
0.96
|
|
Diuretic
|
24 (16)
|
20 (13)
|
0.36
|
|
Mineralocorticoid receptor antagonist
|
6 (4)
|
6 (4)
|
0.90
|
- Variables are expressed as number (%), mean ± SD or medians (interquartile ranges)
- aThe use before the study
- bIndicates atorvastatin, rosuvastatin and pitavastatin