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Table 2 Joinpoint analysis of trends in age-standardized event rates of diabetes-related complications in women with diabetes

From: Trends in diabetes-related complications in Hong Kong, 2001–2016: a retrospective cohort study

ComplicationsEvent rates (per 10,000)Time period 1Time period 2Time period 3
20012016AAPC (95% CI)YearAPC (95% CI)YearAPC (95% CI)YearAPC (95% CI)
CHD
 All ages225.850.8− 9.9 (− 11.8, − 7.9)*2001–2005− 16.3 (− 20.0, − 12.4)*2005–2010− 3.2 (− 8.4, 2.4)2010–2016− 10.8 (− 13.6, − 7.9)*
 20–44 years18.612.5− 2.8 (− 7.6, 2.3)2001–2016− 2.8 (− 7.6, 2.3)    
 45–64 years240.743.0− 10.9 (− 12.1, − 9.8)*2001–2005− 19.6 (− 23.2, − 15.8)*2005–2016− 7.6 (− 8.6, − 6.6)*  
 65–74 years623.594.0− 11.9 (− 12.8, − 10.9)*2001–2005− 18.5 (− 20.4, − 16.5)*2005–2011− 6.0 (− 7.9, − 4.3)*2011–2016− 13.0 (− 14.8, − 11.2)*
 ≥ 75 years727.3223.2− 7.7 (− 8.7, − 6.6)*2001–2005− 10.1 (− 13.0, − 7.1)*2005–2010− 0.83 (− 3.2, 1.6)2010–2016− 11.4 (− 12.5, − 10.3)*
Stroke
 All ages251.364.2− 9.0 (− 9.6, − 8.4)*2001–2004− 16.9 (− 19.0, − 14.8)*2004–2012− 8.5 (− 9.1, − 7.9)*2012–2016− 3.7 (− 5.4, − 2.0)*
 20–44 years41.528.2− 4.4 (− 7.5, − 1.1)*2001–2016− 4.4 (− 7.5, − 1.1)*    
 45–64 years216.152.3− 9.2 (− 10.5, − 8.0)*2001–2006− 16.2 (− 19.3, − 12.9)*2006–2016− 5.5 (− 6.8, − 4.2)*  
 65–74 years590.2100.3− 11.5 (− 13.0, − 10.0)*2001–2004− 19.2 (− 25.7, − 12.2)*2004–2016− 9.5 (− 10.5, − 8.5)*  
 ≥ 75 years1044.8249.7− 9.4 (− 10.7, − 8.0)*2001–2005− 13.5 (− 18.3, − 8.4)*2005–2016− 7.8 (− 8.7, − 6.9)*  
Heart failure
 All ages187.063.9− 7.0 (− 8.0, − 6.0)*2001–2005− 13.0 (− 16.1, − 9.8)*2005–2016− 4.7 (− 5.7, − 3.8)*  
 20–44 years9.213.93.4 (− 2.4, 9.4)2001–20163.4 (− 2.4, 9.4)    
 45–64 years87.425.6− 8.2 (− 10.0, − 6.2)*2001–2006− 15.3 (− 20.0, − 10.3)*2006–2016− 4.4 (− 6.3, − 2.5)*  
 65–74 years371.079.1− 9.8 (− 11.2, − 8.4)*2001–2005− 15.7 (− 20.3, − 10.9)*2005–2016− 7.6 (− 8.8, − 6.4)*  
 ≥ 75 years1273.3454.3− 5.9 (− 6.8, − 5.1)*2001–2016− 5.9 (− 6.8, − 5.1)*    
Hyperglycaemic crisis
 All ages111.320.4− 8.5 (− 10.5, − 6.5)*2001–2016− 8.5 (− 10.5, − 6.5)*    
 20–44 years225.136.0− 8.7 (− 10.8, − 6.6)*2001–2016− 8.7 (− 10.8, − 6.6)*    
 45–64 years22.610.0− 5.9 (− 9.1, − 2.6)*2001–2008− 12.4 (− 17.8, − 6.7)*2008–20160.22 (− 4.5, 5.1)  
 65–74 years8.54.0− 7.5 (− 10.5, − 4.4)*2001–2016− 7.5 (− 10.5, − 4.4)*    
 ≥ 75 years48.76.2− 11.2 (− 15.2, − 6.9)*2001–2006− 28.2 (− 36.8, − 18.4)*2006–2016− 1.3 (− 5.7, 3.4)  
LEA
 All ages21.65.9− 9.1 (− 12.2, − 5.8)*2001–2007− 16.2 (− 22.1, − 9.9)*2007–2016− 4.0 (− 8.1, 0.32)  
 20–44 years9.44.9Not available2001− 2006− 15.5 (− 32.5, 5.9)2008–2016− 0.37 (− 16.5, 18.9)  
 45–64 years11.95.2− 6.4 (− 10.0, − 2.7)*2001–2006− 15.0 (− 23.7, − 5.2)*2006–2016− 1.8 (− 5.5, 2.0)  
 65–74 years39.25.1− 11.8 (− 14.2, − 9.4)*2001–2016− 11.8 (− 14.2, − 9.4)*    
 ≥ 75 years102.214.4− 11.5 (− 12.7, − 10.2)*2001–2016− 11.5 (− 12.7, − 10.2)*    
  1. CHD coronary heart disease, LEA lower-extremity amputation, AAPC average annual percent change, APC annual percent change
  2. * P < 0.05. As no women aged 20–44 years had amputation event in 2007, trend analysis was performed for 2001–2006 and 2008–2016, separately
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Cardiovascular Diabetology

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