Table 1 Joinpoint analysis of trends in age-standardized event rates of diabetes-related complications in men with diabetes
From: Trends in diabetes-related complications in Hong Kong, 2001–2016: a retrospective cohort study
| Complications | Event rates (per 10,000) | Time period 1 | Time period 2 | Time period 3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| 2001 | 2016 | AAPC (95% CI) | Year | APC (95% CI) | Year | APC (95% CI) | Year | APC (95% CI) | |
| CHD | |||||||||
| All ages | 477.3 | 146.0 | − 7.6 (− 10.2, − 5.0)* | 2001–2003 | − 23.1 (− 38.8, − 3.3)* | 2003–2016 | − 5.0 (− 6.0, − 4.0)* | ||
| 20–44 years | 155.9 | 55.1 | − 7.3 (− 15.0, 1.1) | 2001–2003 | − 32.2 (− 66.1, 35.7) | 2003–2016 | − 2.7 (− 6.0, 0.68) | ||
| 45–64 years | 651.9 | 199.8 | − 7.6 (− 9.5, − 5.7)* | 2001–2003 | − 22.6 (− 32.2, − 11.7)* | 2003–2007 | − 7.5 (− 12.9, − 1.9)* | 2007–2016 | − 3.9 (− 4.9, − 3.0)* |
| 65–74 years | 914.3 | 217.1 | − 9.0 (− 11.1, − 6.8)* | 2001–2006 | − 13.7 (− 15.8, − 11.5)* | 2006–2010 | − 3.1 (− 8.4, 2.6) | 2010–2016 | − 8.9 (− 10.5, − 7.3)* |
| ≥ 75 years | 813.3 | 281.1 | − 6.5 (− 8.7, − 4.2)* | 2001–2006 | − 9.3 (− 13.7, − 4.6)* | 2006–2010 | 3.6 (− 4.5, 12.4) | 2010–2016 | − 10.4 (− 12.5, − 8.3)* |
| Stroke | |||||||||
| All ages | 339.5 | 100.9 | − 8.7 (− 9.8, − 7.5)* | 2001–2005 | − 15.3 (− 19.0, − 11.3)* | 2005–2016 | − 6.2 (− 7.1, − 5.2)* | ||
| 20–44 years | 56.2 | 50.3 | − 1.8 (–4.6, 1.1) | 2001–2016 | − 1.8 (− 4.6, 1.1) | ||||
| 45–64 years | 338.2 | 99.7 | − 8.3 (− 9.6, − 7.1)* | 2001–2005 | − 16.3 (− 20.4, − 12.0)* | 2005–2016 | − 5.3 (− 6.1, − 4.4)* | ||
| 65–74 years | 788.5 | 157.5 | − 10.5 (− 11.5, − 9.5)* | 2001–2005 | − 15.4 (− 18.8, − 12.0)* | 2005–2016 | − 8.7 (− 9.5, − 7.9)* | ||
| ≥ 75 years | 1224.8 | 289.0 | − 9.6 (− 10.6, − 8.6)* | 2001–2005 | − 14.8 (− 18.3, − 11.1)* | 2005–2016 | − 7.6 (− 8.3, − 7.0)* | ||
| Heart failure | |||||||||
| All ages | 228.6 | 83.1 | − 6.4 (− 8.0, − 4.7)* | 2001–2005 | − 12.8 (− 18.3, − 7.0)* | 2005–2016 | − 3.9 (− 5.2, − 2.7)* | ||
| 20–44 years | 41.6 | 30.8 | 1.2 (− 2.4, 4.8) | 2001–2016 | 1.2 (− 2.4, 4.8) | ||||
| 45–64 years | 147.5 | 56.6 | − 5.8 (− 8.1, − 3.5)* | 2001–2006 | − 13.7 (− 19.7, − 7.3)* | 2006–2016 | − 1.6 (− 3.7, 0.52) | ||
| 65–74 years | 431.9 | 116.4 | − 8.5 (− 10.0, − 7.1)* | 2001–2009 | − 11.3 (− 13.3, − 9.2)* | 2009–2016 | − 5.3 (− 7.9, − 2.7)* | ||
| ≥ 75 years | 1259.2 | 413.4 | − 6.9 (− 8.7, − 5.1)* | 2001–2005 | − 13.0 (− 19.3, − 6.2)* | ||||
| Hyperglycaemic crisis | |||||||||
| All ages | 81.5 | 33.3 | − 6.6 (− 12.4, − 0.44)* | 2001–2003 | − 30.0 (− 57.9, 16.6) | 2003–2016 | − 2.4 (− 4.9, 0.24) | ||
| 20–44 years | 151.7 | 66.0 | − 3.9 (− 6.2, − 1.5)* | 2001–2016 | − 3.9 (− 6.2, − 1.5)* | ||||
| 45–64 years | 25.4 | 10.1 | − 7.0 (− 10.6, − 3.2)* | 2001–2005 | − 22.3 (− 33.0, − 9.9)* | 2005–2016 | − 0.7 (− 3.5, 2.2) | ||
| 65–74 years | 23.2 | 4.0 | − 12.2 (− 16.3, − 7.9)* | 2001–2003 | − 42.7 (− 60.4, − 17.2)* | 2003–2016 | − 6.2 (− 8.4, − 4.0)* | ||
| ≥ 75 years | 42.3 | 5.5 | − 13.2 (− 17.8, − 8.5)* | 2001–2004 | − 31.4 (− 48.0, − 9.5)* | 2004–2016 | − 8.0 (− 10.7, − 5.3)* | ||
| LEA | |||||||||
| All ages | 36.0 | 11.7 | − 5.8 (− 7.2, − 4.4)* | 2001–2016 | − 5.8 (− 7.2, − 4.4)* | ||||
| 20–44 years | 14.1 | 3.8 | − 7.4 (− 19.5, 6.5) | 2001–2006 | − 8.7 (− 22.4, 7.5) | 2006–2010 | 14.5 (− 17.5, 59.0) | 2010–2016 | − 18.9 (− 27.5, − 9.3)* |
| 45–64 years | 37.5 | 18.4 | − 2.8 (− 4.7, − 0.91)* | 2001–2016 | − 2.8 (− 4.7, − 0.91)* | ||||
| 65–74 years | 48.0 | 16.4 | − 8.0 (− 9.5, − 6.5)* | 2001–2016 | − 8.0 (− 9.5, − 6.5)* | ||||
| ≥ 75 years | 123.0 | 16.6 | − 10.5 (− 12.1, − 8.9)* | 2001–2016 | − 10.5 (− 12.1, − 8.9)* | ||||